Rapid Infliximab Infusion in the Pediatric Population

Shortening infusion times for infliximab administration.

Infliximab-Related Infusion Reactions: Systematic Review

OBJECTIVE Administration of infliximab is associated with a well-recognised risk of infusion reactions. Lack of a mechanism-based rationale for their prevention, and absence of adequate and well-controlled studies, has led to the use of diverse empirical administration protocols. The aim of this study is to perform a systematic review of the evidence behind the strategies for preventing infusio...

Severe hidradenitis suppurativa treated with infliximab infusion.

A 17-year-old male patient with a 3-year history of hidradenitis suppurativa presented to our dermatology clinic for more effective treatment. Areas of involvement included the medial aspect of the thighs, scrotum, buttocks, and inframammary folds. His axillae were spared. He also had a pilonidal cyst and nodulocystic acne. A diagnosis of hidradenitis suppurativa was rendered. The patient’s sym...

Autoimmune hemolytic anemia associated with infliximab infusion in ulcerative colitis

Infliximab is a monoclonal antibody that antagonizes the activity of tumor necrosis factor alpha to induce and maintain remission in patients with inflammatory bowel disease. Adverse effects associated with Infliximab infusions include infusion reactions, risk of infections, development of hematological malignancies, and pancytopenia. Autoimmune hemolytic anemia has rarely been reported in ulce...

Profile of infliximab in the treatment of pediatric Crohn’s disease

In recent years, a novel biologic therapy with monoclonal antibodies against tumor necrosis factor-alpha has revolutionized the treatment of Crohn's disease. Infliximab, the first biologic agent, has been demonstrated to considerably improve both clinical and endoscopic outcomes. In view of the growing popularity of infliximab in the management of Crohn's disease, we review the profile of the a...